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Artificial Systems Meet Biology

Biointerfaces, Bioelectronics
(바이오 인터페이스, 바이오 반도체소자)
Computers meet humans

​​The ABLE lab is pioneering a new area of research entitled “bioelectrochemical interfaces” that connect computers and humans through electrochemistry. We have demonstrated that these interfaces can be integrated into a wide range of biomaterials and bioelectronic devices to convert digital signals (electrons) into biochemical signals (signaling molecules). Especially, our neural probes enabled an electrochemical modulation of neuronal activities and animal behaviors for the first time.  We are extending this approach to digitally monitor and treat diseases across the nervous, gastrointestinal, and cardiovascular systems. 

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[대표논문 리스트]

Nat. Nanotechnol., 15, 690-697 (2020), Adv. Func. Mater (2025), Angew. Chem. Int. Ed., e202508192 (2025), Adv. Mat. Inter., e00417 (2025), Angew. Chem. Int. Ed., 49, 14753 (2015)

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Microbe-based CO2 Conversion
(미생물 기반 이산화탄소 변환 시스템)
Energy devices meet microorganisms

​​​The ABLE lab is launching new efforts to develop chemical manufacturing platforms comprised of synthetic materials and microorganisms. We engineer the interface between conventional energy devices and microorganisms to power the metabolic pathways of microorganisms sustainably. These biohybrid platforms will enable the sustainable production of chemical fuels from CO2. 

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[대표논문 리스트]

Angew. Chem. Int. Ed., 60, 20325 (2021),  Angew. Chem. Int. Ed., 60, 18295 (2021)​​​

Microbes_short.png

Biohybrid Materials

(유전자 전달체, 바이오촉매)

Synthetic materials meet biomolecules​

The ABLE lab is discovering new materials by interfacing synthetic materials with biomolecules. Representative examples include enzyme-like nanocatalysts (for hydrogen evolution, CO2 reduction, and biomass conversion) and functional adeno-associated virus (AAV) vectors (for gene or drug delivery). We design, synthesize, and characterize these new material systems at the atomic scale and utilize them as platforms for biocatalysis and gene therapy.

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[대표논문 리스트]

Nat. Rev. Methods Primers 2, 92 (2022), Nano Lett., 20, 6353 (2020), Nat. Commun., 6, 8253 (2015), J. Am. Chem. Soc. 136, 7435 (2014), J. Am. Chem. Soc. 136, 4201 (2014)

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